Article

SARS-CoV-2 variants of concern remain dependent on IFITM2 for efficient replication in human lung cells

2021-11-17

Abstract excerpt

<h4>ABSTRACT</h4> It has recently been shown that an early SARS-CoV-2 isolate (NL-02-2020) hijacks interferon-induced transmembrane proteins (IFITMs) for efficient replication in human cells. To date, several “Variants of Concern” (VOCs) showing increased infectivity and resistance to neutralization have emerged and globally replaced the early viral strains. Here, we determined whether the four SARS-CoV-2 VOCs (A...

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Literature Corpus work: 8d8d92f1-a8b4-5fb0-bad3-26b798e8364f
DOI: 10.1101/2021.11.17.468942

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