Article

Recovering rearranged cancer chromosomes from karyotype graphs

2019-11-05

Abstract excerpt

Many cancer genomes are extensively rearranged with highly aberrant chromosomal karyotypes. Structural and copy number variations in cancer genomes can be determined via abnormal mapping of sequenced reads to the reference genome. Recently it became possible to reconcile both of these types of large-scale variations into a karyotype graph representation of the rearranged cancer genomes. Such a representation, howe...

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Identifiers and source

Literature Corpus work: 6735476f-fb16-58fa-8f7b-dc360a556a90
DOI: 10.1101/831057

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