Article

Prediction of the 3D cancer genome from genomic rearrangements using InfoHiC

2022-08-03

Abstract excerpt

Although cancer genomes often contain complex genomic rearrangements, its impact on tumorigenesis is still unclear, especially when they are involved in non-coding regions. Understanding 3D genome architecture is crucial for uncovering the impacts of genomic rearrangements. Here, we present InfoHiC, a method for predicting 3D genome folding and cancer Hi-C from complex genomic rearrangements. InfoHiC provides dist...

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Identifiers and source

Literature Corpus work: 55f1cf0e-8462-519a-a356-96355d516a19
DOI: 10.1101/2022.08.02.502462

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