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Article

Estimation of rearrangement phylogeny for cancer genomes.

Genome research - 1 Feb 2012

Greenman Chris D, Pleasance Erin D, Newman Scott, Yang Fengtang, Fu Beiyuan, Nik-Zainal Serena, Jones David, Lau King Wai, Carter Nigel, Edwards Paul A W, Futreal P Andrew, Stratton Michael R, Campbell Peter J

Abstract excerpt

Cancer genomes are complex, carrying thousands of somatic mutations including base substitutions, insertions and deletions, rearrangements, and copy number changes that have been acquired over decades. Recently, technologies have been introduced that allow generation of high-resolution, comprehensive catalogs of somatic alterations in cancer genomes. However, analyses of these data sets generally do not indicate...

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PMID: 21994251
DOI: 10.1101/gr.118414.110
PMCID: PMC3266042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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