Article
Reconstructing tumor genome architectures.
Bioinformatics (Oxford, England) - 1 Oct 2003
Raphael Benjamin J, Volik Stanislav, Collins Colin, Pevzner Pavel A
Abstract excerpt
Although cancer progression is often associated with genome rearrangements, little is known about the detailed genomic architecture of tumor genomes. The attempt to reconstruct the genomic organization of a tumor genome recently resulted in the development of the End Sequence Profiling (ESP) technique, and the application of this technique to human MCF7 tumor cells. We formulate the ESP Genome Reconstruction...
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