Article

Machine-guided design of synthetic cell type-specific <i>cis</i> -regulatory elements

2023-08-09

Abstract excerpt

Cis -regulatory elements (CREs) control gene expression, orchestrating tissue identity, developmental timing, and stimulus responses, which collectively define the thousands of unique cell types in the body. While there is great potential for strategically incorporating CREs in therapeutic or biotechnology applications that require tissue specificity, there is no guarantee that an optimal CRE for an intended purpo...

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Literature Corpus work: 66cbe8de-dd85-5224-827b-beeb1d411020
DOI: 10.1101/2023.08.08.552077

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