Article

Active learning of enhancer and silencer regulatory grammar in photoreceptors

2023-08-22

Abstract excerpt

<h4>ABSTRACT</h4> Cis -regulatory elements (CREs) direct gene expression in health and disease, and models that can accurately predict their activities from DNA sequences are crucial for biomedicine. Deep learning represents one emerging strategy to model the regulatory grammar that relates CRE sequence to function. However, these models require training data on a scale that exceeds the number of CREs in the geno...

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Literature Corpus work: ae4c5f34-01d9-52fb-ade4-af296b16b1e8
DOI: 10.1101/2023.08.21.554146

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