Article

Evolutionary conditioning enables guided generation of functionally diverse enhancers

2026-04-15

Abstract excerpt

Deep learning has been instrumental in our understanding of how enhancers encode regulatory information in their DNA sequence and has demonstrated preliminary success with enhancer design. However, the prevailing approach for enhancer design, cell type label conditioning, depends on labeled data from massively parallel reporter assays, which only exists for a handful of cell types. We propose EnhancAR, an autoregr...

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Literature Corpus work: 51944de7-9fae-5f79-b2bb-1b325af575fe
DOI: 10.64898/2026.04.13.718170

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