Article
Plasticity and Functional Heterogeneity of Cancer-Associated Fibroblasts
29 Jul 2025
Abstract excerpt
Tumor heterogeneity and plasticity enable adaptation to metastatic microenvironments and resistance to therapies. Recent progress in single-cell analyses has permitted detailed characterization of the complexity and diversity of the different tumor components in multiple tumor types. Cancer-associated fibroblasts (CAF) are a central component of the tumor microenvironment and play critical roles in cancer...
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