Article
Recent advances in cancer-associated fibroblast: Biomarkers, signaling pathways, and therapeutic opportunities.
Chinese medical journal - 20 Mar 2024
Zhou Donger, Zheng Lei
Abstract excerpt
ABSTRACT: Anti-cancer therapies usually focus on tumor cells, but non-tumor stromal components in the tumor microenvironment also play vital roles in tumor initiation and progression, which may be the prognostic factors and potential therapeutic targets. Cancer-associated fibroblasts (CAFs) are the essential component in the tumor environment, exhibiting high heterogeneity in their cell origin and phenotype with...
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