Article

Deployment of non-canonical splicing in tunicate genomes is mediated by divergent U2AF function and re-patterning of snRNA m6A modification

2025-08-17

Abstract excerpt

In eukaryotes, the critical function of the spliceosome is to remove introns from newly transcribed pre-messenger RNA to produce functional mRNA. Spliced segments normally begin with a GT and end with an AG, and precise intron removal relies on the recognition of terminal dinucleotides by the spliceosomal RNA (snRNA) and by the U2AF heterodimer. Here, we reveal how the modification of these molecules was instrumen...

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Literature Corpus work: 664c6c1f-f560-52bd-a0ce-0ee55cc76965
DOI: 10.1101/2025.08.15.670264

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Deployment of non-canonical splicing in tunicate genomes is mediated by divergent U2AF function and re-patterning of snRNA m6A modificationDOI 10.1101/2025.08.15.670264Read

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