Article

Is intron removal by recursive splicing necessitated by the evolution of genomic gigantism?

2024-12-16

Abstract excerpt

Splicing of introns is an important step that pre-mRNA transcripts undergo during processing in the nucleus to become mature mRNAs. Although long thought to occur in a single step, introns are now also known to be removed in multiple steps through a process called recursive splicing. This non-canonical form of splicing is hypothesized to increase splicing fidelity, particularly in longer introns. In species that h...

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Literature Corpus work: 690e6950-e7cc-5e1f-9275-e5b4a459b495
DOI: 10.1101/2024.12.11.627982

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