Article
Alternative splicing of U12-type introns.
Frontiers in bioscience : a journal and virtual library - 1 Jan 2008
Chang Wen-Cheng, Chen Hung-Hsi, Tarn Woan-Yuh
Abstract excerpt
Precise removal of introns from metazoan precursor mRNAs is critical for gene expression. Nevertheless, alternative splicing provides a means for higher eukaryotes to increase genomic complexity and proteome diversity and to regulate certain cellular functions. The presence of rare U12-type pre-mRNA introns in eukaryotic genomes further complicates splicing events. In this review, we discuss the mechanism of...
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