Article
AAV-miR-124 enhances endogenous alveolar epithelial regenerative plasticity and reverses bleomycin-induced pulmonary fibrosis
2026-08-04
Abstract excerpt
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease characterized by irreversible destruction of the alveolar epithelium and impaired regeneration. Although current therapies slow disease progression, they do not restore functional alveoli, highlighting the need for regenerative approaches that promote endogenous lung repair. Here, we performed the first unbiased functional screen of 2,0...
Topics
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- Cancer Diagnosis and Treatment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- IL-33, ST2, and ILC Pathways
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Macrophage Migration Inhibitory Factor
- Medical Imaging and Pathology Studies
- Neonatal Respiratory Health Research
- Occupational and environmental lung diseases
Identifiers and source
- Literature Corpus work
- 65ff6586-6574-5bac-a335-c6fe149280fb
- DOI
- 10.64898/2026.08.03.741463
