Article

RNA-sequencing comparison of pneumonectomy and bleomycin reveals anti-fibrotic mechanisms of lung fibroblasts

2022-12-02

Abstract excerpt

<h4>Background: </h4> Idiopathic pulmonary fibrosis (IPF) is characterized by pathological accumulation of scar tissue in the lung parenchyma. Many of the processes that are implicated in fibrosis, such as matrix deposition also occur following pneumonectomy (PNX). However, fibrosis does not occur. Since fibroblasts are the major cell type responsible for extracellular matrix production, we hypothesized that compa...

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Literature Corpus work: aa361171-ccd2-59b6-9a8e-ae7cbe409ec5
DOI: 10.21203/rs.3.rs-2306746/v1

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