Article
Immunity-and-Matrix-Regulatory Cells Derived from Human Embryonic Stem Cells Safely and Effectively Treat Mouse Lung Injury and Fibrosis
2020-04-16
Abstract excerpt
Lung injury and fibrosis represent the most significant outcomes of severe and acute lung disorders, including COVID-19. However, there are still no effective drugs to treat lung injury and fibrosis. In this study, we report the generation of clinical-grade human embryonic stem cells (hESCs)-derived immunity- and matrix-regulatory cells (IMRCs) produced under good manufacturing practice (GMP) requirements, that ca...
Topics
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- Dermatological and COVID-19 studies
- Extracellular vesicles in disease
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Medical Imaging and Pathology Studies
- Mesenchymal stem cell research
- Neonatal Respiratory Health Research
- Pleural and Pulmonary Diseases
- Pulmonary Hypertension Research and Treatments
Identifiers and source
- Literature Corpus work
- 04325cf3-fa00-5037-b9b5-783b2bf3a1f5
- DOI
- 10.1101/2020.04.15.042119
