Article
Lobe-resolved transcriptomic profiling of post-pneumonectomy lung growth reveals Fgfr2b-dependent epithelial maintenance and control of fibrotic remodeling
2026-06-25
Abstract excerpt
<title>Abstract</title> <p> Even though compensatory lung growth after pneumonectomy is well recognized in rodents, regenerative growth in the adult human lung has gained significant interest recently. Defining the molecular programs that drive this response in mice may therefore provide insight into mechanisms of adult lung regeneration. We hypothesized that compensatory lung growth after pneumonectomy is not a...
Topics
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- Chronic Obstructive Pulmonary Disease (COPD) Research
- Congenital Diaphragmatic Hernia Studies
- Congenital heart defects research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Medical Imaging and Pathology Studies
- Neonatal Respiratory Health Research
- Occupational and environmental lung diseases
- Renal and related cancers
Identifiers and source
- Literature Corpus work
- 8df4b4cf-e88f-55f7-b645-f0546c27f36d
- DOI
- 10.21203/rs.3.rs-10046576/v1
