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Lobe-resolved transcriptomic profiling of post-pneumonectomy lung growth reveals Fgfr2b-dependent epithelial maintenance and control of fibrotic remodeling

2026-06-25

Abstract excerpt

<title>Abstract</title> <p> Even though compensatory lung growth after pneumonectomy is well recognized in rodents, regenerative growth in the adult human lung has gained significant interest recently. Defining the molecular programs that drive this response in mice may therefore provide insight into mechanisms of adult lung regeneration. We hypothesized that compensatory lung growth after pneumonectomy is not a...

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Literature Corpus work
8df4b4cf-e88f-55f7-b645-f0546c27f36d
DOI
10.21203/rs.3.rs-10046576/v1
Open publication

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Lobe-resolved transcriptomic profiling of post-pneumonectomy lung growth reveals Fgfr2b-dependent epithelial maintenance and control of fibrotic remodelingDOI 10.21203/rs.3.rs-10046576/v1
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