Article

PRDX4 regulates AMs cell activity through the AKT/NF-κB pathway to inhibit the progress of pulmonary fibrosis

2023-08-04

Abstract excerpt

<h4>Background: </h4> Idiopathic pulmonary fibrosis (IPF) is a fatal disease that leads to severe lung fibrosis, and PRDX4 expressed highly in AMs may be closely related to the process of fibrosis progression. This study investigates the function and molecular mechanisms of the potential therapeutic target PRDX4 in idiopathic pulmonary fibrosis (IPF). Methods This study utilized single-cell RNA sequencing (scRNA-...

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Literature Corpus work: 5a1e8b66-6393-5296-9555-e9d74ca90d2f
DOI: 10.21203/rs.3.rs-3196233/v1

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