Article

Germline mutations and developmental mosaicism underlying<i>EGFR</i>-mutant lung cancer

2023-09-29

Abstract excerpt

While the development of multiple primary tumors in smokers with lung cancer can be attributed to carcinogen-induced field cancerization, the occurrence of multiple primary tumors in individuals with EGFR -mutant lung cancer who lack known environmental exposures remains unexplained. We identified ten patients with early-stage, resectable non-small cell lung cancer who presented with multiple anatomically distinct...

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Literature Corpus work: 65a31351-7abc-55a3-9631-ae4b4e6293c9
DOI: 10.1101/2023.09.28.23296274

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