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Protective human anti-poxvirus monoclonal antibodies are generated from rare memory B cells isolated by multicolor antigen tetramers

2022-06-05

Abstract excerpt

Smallpox, an epidemic disease caused by Orthopoxvirus variola , was eradicated worldwide through immunization. The immunization against smallpox was discontinued in 1980. However, incidences of monkeypox virus infection in humans have occurred sporadically, and there is also great fear that engineered forms of poxvirus could be used as biological weapons. Therefore, monoclonal antibodies against poxvirus are in u...

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Literature Corpus work
65332820-b114-5d8a-b1e4-3fb783849a9f
DOI
10.1101/2022.06.04.494786
Open publication

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Protective human anti-poxvirus monoclonal antibodies are generated from rare memory B cells isolated by multicolor antigen tetramersDOI 10.1101/2022.06.04.494786
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