Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Facile Discovery of a Diverse Panel of Anti-Ebola Virus Antibodies by Immune Repertoire Mining.

Scientific reports - 10 Sept 2015

Wang Bo, Kluwe Christien A, Lungu Oana I, DeKosky Brandon J, Kerr Scott A, Johnson Erik L, Tanno Hidetaka, Lee Chang-Han, Jung Jiwon, Rezigh Alec B, Carroll Sean M, Reyes Ann N, Bentz Janelle R, Villanueva Itamar, Altman Amy L, Davey Robert A, Ellington Andrew D, Georgiou George

Abstract excerpt

The ongoing evolution of Ebolaviruses poses significant challenges to the development of immunodiagnostics for detecting emergent viral variants. There is a critical need for the discovery of monoclonal antibodies with distinct affinities and specificities for different Ebolaviruses. We developed an efficient technology for the rapid discovery of a plethora of antigen-specific monoclonal antibodies from immunized...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibody Formation
Share to Cross Reactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ebolavirus

Share to Hemorrhagic Fever, Ebola

Share to Immunization

Share to Immunoglobulin Heavy Chains

Share to Immunoglobulin Light Chains

Share to Immunoglobulin Variable Region

Source

Open in PubMed Open full text

Identifiers

PMID: 26355042
DOI: 10.1038/srep13926
PMCID: PMC4564727

Genes

PLN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Facile Discovery of a Diverse Panel of Anti-Ebola Virus Antibodies by Immune Repertoire Mining.PMID 26355042Read ↗

Naïve antibody library derived monoclonal antibody against VP35 of Ebola virusSemantic proximity Read ↗

Systematic analysis of human antibody response to ebolavirus glycoprotein reveals high prevalence of neutralizing public clonotypesSemantic proximity Read ↗

Molecular characterization of the monoclonal antibodies composing ZMAb: a protective cocktail against Ebola virus.Semantic proximity Read ↗

Human antibody cocktail deploys multiple functions to confer pan-ebolavirus protectionSemantic proximity Read ↗

Macaque Monoclonal Antibodies Targeting Novel Conserved Epitopes within Filovirus GlycoproteinSemantic proximity Read ↗

Exploiting V-Gene Bias for Rapid, High-Throughput Monoclonal Antibody Isolation from HorsesSemantic proximity Read ↗

In Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse ModelSemantic proximity Read ↗

Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site.Semantic proximity Read ↗

Monoclonal antibodies for the treatment of Ebola virus disease.Semantic proximity Read ↗

Functional characterization and lineage analysis of broadly neutralizing human antibodies against dengue virus identified by single B cell transcriptomicsSemantic proximity Read ↗

Phage Display Approaches for the Isolation of Monoclonal Antibodies Against Dengue Virus Envelope Domain III from Human and Mouse Derived LibrariesSemantic proximity Read ↗

Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalkSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.