Article

Oligodendrocyte subtype diversity underlines clinical progression in Parkinson’s disease

2026-05-18

Abstract excerpt

<h4>ABSTRACT</h4> Despite growing evidence for glial involvement in Parkinson’s disease, oligodendrocyte dysfunction remains poorly defined. To address this gap, we compared single-cell RNA sequencing from a mouse model of α-synuclein aggregation pathology with fresh human brain tissue from deep brain stimulation surgery to build a cross-species framework of disease progression. In total, we profiled over 200,000...

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Literature Corpus work: 6531d139-9af7-588b-945b-faf35f4c3dbd
DOI: 10.64898/2026.05.15.724963

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