Article

Transcriptomic changes in oligodendrocytes and precursor cells predicts clinical outcomes of Parkinson’s disease

2023-05-12

Abstract excerpt

Several prior studies have proposed the involvement of various brain regions and cell types in Parkinson’s disease (PD) pathology. Here, we performed snRNA-seq on the prefrontal cortex and anterior cingulate regions from post-mortem control and PD brain tissue. We found a significant association of oligodendrocytes (ODCs) and oligodendrocyte precursor cells (OPCs) with PD-linked risk loci and report several dysreg...

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Literature Corpus work: a5bcea06-434d-54c5-96da-db4d2384f84f
DOI: 10.1101/2023.05.11.540329

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