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Changes in oligodendroglial subpopulations in Parkinson’s disease

14 Sept 2023

Abstract excerpt

Parkinson's disease (PD) is characterized by a selective loss of dopaminergic neurons. While most research on PD conducted to date has focused on neurons and, to a certain extent, glia, few studies have investigated changes in oligodendroglia. Here, we investigated the heterogeneity of oligodendrocytes from PD patients compared with those of control cases by analyzing single-nuclei transcriptomes. These analyses...

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PMID: 37710343
DOI: 10.1186/s13041-023-01055-5

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