Article

Germline polygenic score for prostate cancer aggressiveness

2026-05-10

Abstract excerpt

<h4>Background</h4> Risk stratification for prostate cancer (PCa) progression or aggressiveness is often based on clinicopathologic features, some of which may be influenced by genetic factors. We developed a novel, germline polygenic risk score (PRSagg) to predict likelihood of developing aggressive PCa. <h4>Methods</h4> PRSagg was developed using data from 38,688 patients with PCa (case-only analysis) from the...

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Literature Corpus work: 6528d3aa-2434-521c-80ab-68e6e04d37be
DOI: 10.64898/2026.05.07.26352488

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