Article

Precision Prostate Cancer Screening with a Polygenic Risk Score

2020-08-25

Abstract excerpt

Prostate cancer (PC) is the second-most common type of cancer and the fifth-leading cause of cancer-related death in men worldwide. Genome-wide association studies have identified numerous genetic variants (SNPs) independently associated with PC. The effects of such SNPs can be combined into a single polygenic risk score (PRS). Stratification of men according to PRS could be applied in secondary prevention. We aim...

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Literature Corpus work: 49b242f0-ab54-5c67-9e3e-7d14b3f3b73e
DOI: 10.1101/2020.08.23.20180570

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