Article

Distinct TAF15 amyloid filament folds define multiple subtypes of FTLD-TAF15

2026-01-12

Abstract excerpt

<h4>ABSTRACT</h4> Neurodegenerative diseases are characterised by the assembly of a limited number of disease-specific proteins into amyloid filaments, which form intracellular inclusions or extracellular deposits in the central nervous system (CNS) 1,2 . We previously found that amyloid filaments of TATA-binding protein-associated factor 15 (TAF15) characterise a subtype of frontotemporal lobar degeneration wit...

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Literature Corpus work: 64d26b33-4d59-5107-a70d-e989589cfbfe
DOI: 10.64898/2026.01.12.698957

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