Article

Structure-based Classification of Tauopathies

2021-05-28

Abstract excerpt

<h4>ABSTRACT</h4> Ordered assembly of the tau protein into filaments characterizes multiple neurodegenerative diseases, which are called tauopathies. We previously reported that by electron cryo-microscopy (cryo-EM), tau filament structures from Alzheimer’s disease (1,2), chronic traumatic encephalopathy (CTE) (3), Pick’s disease (4) and corticobasal degeneration (CBD) (5) are distinct. Here we show that the stru...

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Literature Corpus work: fd13e6b3-758a-5ee4-b5f9-f6738f535341
DOI: 10.1101/2021.05.28.446130

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