Article

The transcription factor Traffic jam orchestrates the somatic piRNA pathway in <i>Drosophila</i> ovaries

2024-09-10

Abstract excerpt

The PIWI-interacting RNA (piRNA) pathway is essential for transposable element (TE) silencing in animal gonads. While the transcriptional regulation of piRNA pathway components in germ cells has been documented in mice and flies, their control in somatic cells of Drosophila ovaries remains unresolved. Here, we demonstrate that Traffic jam (Tj), the Drosophila orthologue of large Maf transcription factors in mamm...

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Literature Corpus work: 649c6ec7-69f1-58d8-a970-92737bee9761
DOI: 10.1101/2024.09.10.612307

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