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<i>putzig</i> safeguards genome integrity by contributing to the Piwi-mediated repression of transposon activity in the female germline of <i>Drosophila</i> in a two-tiered fashion

2026-03-13

Abstract excerpt

Genome integrity in the germline is jeopardized by the activity of transposable elements (TEs). Transposon activity is kept in check by the Piwi-piRNA pathway, which silences TEs post-transcriptionally in the cytoplasm as well as co-transcriptionally in the nucleus. piRNAs derive from long precursor transcripts originating at piRNA-loci by non-conventional transcription. They are processed in the cytoplasm and loa...

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Literature Corpus work
35e0ca45-e3ce-58aa-b64d-4daf6c0c4fba
DOI
10.64898/2026.03.11.711025
Open publication

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<i>putzig</i> safeguards genome integrity by contributing to the Piwi-mediated repression of transposon activity in the female germline of <i>Drosophila</i> in a two-tiered fashionDOI 10.64898/2026.03.11.711025
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