Back to search

Article

Unistrand piRNA clusters are an evolutionarily conserved mechanism to suppress endogenous retroviruses across the <i>Drosophila</i> genus

2023-02-27

Abstract excerpt

<h4>SUMMARY</h4> The PIWI-interacting RNA (piRNA) pathway prevents endogenous genomic parasites, transposable elements, from damaging the genetic material of animal gonadal cells. Specific regions in the genome, called piRNA clusters, are thought to define each species’ piRNA repertoire and therefore its capacity to recognize and silence specific transposon families. The unistrand cluster flamenco ( flam ) is e...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
f4a3e4be-7d59-5fe2-96d7-17e363e33921
DOI
10.1101/2023.02.27.530199
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Unistrand piRNA clusters are an evolutionarily conserved mechanism to suppress endogenous retroviruses across the <i>Drosophila</i> genusDOI 10.1101/2023.02.27.530199
piRNA-mediated gene regulation and adaptation to sex-specific transposon expression in <i>D. melanogaster</i> male germlineSemantic proximity
Specialized piRNA pathways act in germline and somatic tissues of the Drosophila ovary.Semantic proximity
Conserved but mechanistically diverse piRNA defence against <i>gypsy</i> LTR retrotransposons in insect ovariesSemantic proximity
Mechanistic divergence of piRNA biogenesis in DrosophilaSemantic proximity
Maelstrom Represses Canonical Polymerase II Transcription within Bi-Directional piRNA Clusters in <i>Drosophila melanogaster</i>Semantic proximity
FlaHMM: unistrand <i>flamenco</i> -like piRNA cluster prediction in <i>Drosophila</i> species using hidden Markov modelsSemantic proximity
Trapping a somatic endogenous retrovirus into a germline piRNA cluster immunizes the germline against further invasionSemantic proximity
Rapid evolutionary diversification of the <i>flamenco</i> locus across simulans clade <i>Drosophila</i> speciesSemantic proximity
The piRNA pathway mediates transcriptional silencing of LTR retrotransposons in ovaries and somatic tissues of <i>Aedes</i> mosquitoesSemantic proximity
The Drosophila OSC Genome: A Resource for Studies of Transposon and piRNA BiologySemantic proximity
Chromatin profiling identifies transcriptional readthrough as a conserved mechanism for piRNA cluster biogenesis in mosquitoesSemantic proximity
piRNAs are abundant in the early embryo of the crustacean <i>Parhyale hawaiensis</i>Semantic proximity
Select a neighboring publication to make it the new centre.