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The histone demethylase KDM3 prevents auto-immune piRNAs production in <i>Drosophila</i>

2022-06-03

Abstract excerpt

<h4>SUMMARY</h4> In animals, genome integrity of the germ line is protected from transposable element (TE) activity by small, non-coding, dedicated RNAs acting as an immune system against TEs, and called PIWI-interacting RNAs (piRNAs) 1,2 . In Drosophila, the production of piRNAs is initiated from heterochromatic loci containing remnants of TEs and enriched in histone H3 trimethylated on lysine 9 (H3K9me3) 3–5...

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Literature Corpus work
9d0bb9f6-865b-53e3-8a20-845cf316ad08
DOI
10.1101/2022.06.02.494511
Open publication

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The histone demethylase KDM3 prevents auto-immune piRNAs production in <i>Drosophila</i>DOI 10.1101/2022.06.02.494511
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