Article
A regulatory circuit for piwi by the large Maf gene traffic jam in Drosophila.
Nature - 29 Oct 2009
Saito Kuniaki, Inagaki Sachi, Mituyama Toutai, Kawamura Yoshinori, Ono Yukiteru, Sakota Eri, Kotani Hazuki, Asai Kiyoshi, Siomi Haruhiko, Siomi Mikiko C
Abstract excerpt
PIWI-interacting RNAs (piRNAs) silence retrotransposons in Drosophila germ lines by associating with the PIWI proteins Argonaute 3 (AGO3), Aubergine (Aub) and Piwi. piRNAs in Drosophila are produced from intergenic repetitive genes and piRNA clusters by two systems: the primary processing pathway and the amplification loop. The amplification loop occurs in a Dicer-independent, PIWI-Slicer-dependent manner....
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