Article

Female LSD1 Conditional Knockout Mice Have an Increased Bone Mass

2022-06-27

Abstract excerpt

Osteoclasts are large multinucleated cells that degrade bone mineral and extracellular matrix. Investigating the mechanisms by which osteoclast differentiation is epigenetically regulated is a key to understanding the pathogenesis of skeletal related diseases such as periodontitis and osteoporosis. Lysine specific demethylase 1 (LSD1/KDM1A) is a member of the histone demethylase family that regulates gene expressi...

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Literature Corpus work: 643962a6-6656-5bbe-a3cf-799fd8894551
DOI: 10.1101/2022.06.25.497607

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