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Article

Genetic regulation of osteoclast development and function.

Nature reviews. Genetics - 1 Aug 2003

Teitelbaum Steven L, Ross F Patrick

Abstract excerpt

Osteoclasts are the principal, if not exclusive, bone-resorbing cells, and their activity has a profound impact on skeletal health. So, disorders of skeletal insufficiency, such as osteoporosis, typically represent enhanced osteoclastic bone resorption relative to bone formation. Prevention of pathological bone loss therefore depends on an appreciation of the mechanisms by which osteoclasts differentiate from...

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Identifiers

PMID: 12897775
DOI: 10.1038/nrg1122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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