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Article

Id1 represses osteoclast-dependent transcription and affects bone formation and hematopoiesis.

PloS one - 24 Nov 2009

Chan April S, Jensen Kristian K, Skokos Dimitris, Doty Stephen, Lederman Hannah K, Kaplan Rosandra N, Rafii Shahin, Rivella Stefano, Lyden David

Abstract excerpt

BACKGROUND: The bone-bone marrow interface is an area of the bone marrow microenvironment in which both bone remodeling cells, osteoblasts and osteoclasts, and hematopoietic cells are anatomically juxtaposed. The close proximity of these cells naturally suggests that they interact with one another, but these interactions are just beginning to be characterized. METHODOLOGY/PRINCIPAL FINDINGS: An Id1(-/-) mouse...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19956687
DOI: 10.1371/journal.pone.0007955
PMCID: PMC2776978

Genes

CTSK

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