Article

γ-Amino Carboxylic Acid Modification Enhances the Efficacy of PNAs Targeting miR-221-3p in A549 Cells

2025-06-19

Abstract excerpt

<h4>ABSTRACT</h4> Peptide nucleic acids (PNAs) are versatile tools for diagnostic and therapeutic applications, including gene regulation and miRNA targeting. However, their therapeutic potential is often limited by challenges such as biological efficacy. To address this, PNAs offer a key advantage over other nucleic acids—their ease of modification, which allows for enhanced properties. In this study, we introdu...

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Literature Corpus work: 6427ee1c-8bdf-5d5f-9a64-1a53baacda83
DOI: 10.1101/2025.06.15.659802

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