Article

Turing miRNA Into Infinite Coordination Supermolecule: A General and Enabling Nanoengineering Strategy for Resurrecting Nuclear Acid Therapeutics

2021-11-16

Abstract excerpt

<title>Abstract</title> <p>Background Clinical translation of therapeutic nuclear acid, particularly those targeting tumor progression, has been hampered by the intrinsic weaknesses of nuclear acid therapeutic including poor systemic stability, rapid clearance, low membrane permeability and lack of targeting ability. Small nuclear acid engineered into carrier-free nanodrugs with structural stability and disease...

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Literature Corpus work: bdf14b9e-48c6-5cf2-b0bf-8e815954854e
DOI: 10.21203/rs.3.rs-1054917/v1

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