Article

LDLR-mediated targeting and productive uptake of siRNA-peptide ligand conjugates <i>in vitro</i> and <i>in vivo</i>

2023-02-03

Abstract excerpt

<h4>ABSTRACT</h4> siRNAs have become one of the most promising therapeutic agents because of their specificity and their potential to modulate the expression of gene-related diseases. Any gene of interest can be potentially up or down-regulated, making RNA-based technology the healthcare breakthrough of our era. However, the functional and specific delivery of siRNAs into tissues of interest and into the cytosol...

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Literature Corpus work: 19f846c5-5c49-531d-ac4b-3f557b38b2be
DOI: 10.1101/2023.02.03.526778

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