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Biodegradable Poly( <i>β</i> -amino amide)s Enable Efficient RNA Delivery and Spleen Targeting

2025-03-11

Abstract excerpt

RNA therapeutics are emerging as transformative modalities in clinical applications and have become a key area in life science research. While lipid nanoparticles (LNPs) have become the leading platform for RNA delivery in preventive and therapeutic products, they still face significant challenges in achieving efficient extrahepatic delivery and maintaining long term shelf stability. Here we report the development...

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Literature Corpus work
d20fa769-2a4e-55c7-a4e2-7c9afb8f3423
DOI
10.1101/2025.03.03.641302
Open publication

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Biodegradable Poly( <i>β</i> -amino amide)s Enable Efficient RNA Delivery and Spleen TargetingDOI 10.1101/2025.03.03.641302
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