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OpenAntigens: a structure-aware database for antigen construct design across the human cell-surface and secreted proteome

2026-08-04

Abstract excerpt

Choosing which region of a protein to express remains poorly standardized in antibody discovery, recombinant reagent generation, structural biology and computational binder design. For human cell-surface and secreted proteins, this requires reconciling topology, processing, predicted and experimental structure, modifications, interaction partners, orthologs, paralogs and cross-reactivity risk before ordering DNA....

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Identifiers and source

Literature Corpus work
64203ed1-8cd4-5103-9e9f-41e5e8af0318
DOI
10.64898/2026.07.30.741735
Open publication

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OpenAntigens: a structure-aware database for antigen construct design across the human cell-surface and secreted proteomeDOI 10.64898/2026.07.30.741735
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