Identifying developability risks for clinical progression of antibodies using high-throughput in vitro and in silico approaches

Abstract excerpt

With the growing significance of antibodies as a therapeutic class, identifying developability risks early during development is of paramount importance. Several high-throughput in vitro assays and in silico approaches have been proposed to de-risk antibodies during early stages of the discovery process. In this review, we have compiled and collectively analyzed published experimental assessments and...

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