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PROSCA: an online platform for humanized scaffold mining facilitating rational protein engineering

13 May 2024

Abstract excerpt

Protein scaffolds with small size, high stability and low immunogenicity show important applications in the field of protein engineering and design. However, no relevant computational platform has been reported yet to mining such scaffolds with the desired properties from massive protein structures in human body. Here, we developed PROSCA, a structure-based online platform dedicated to explore the space of the...

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PMID: 38738624
DOI: 10.1093/nar/gkae384

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