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CellectSeq: In Silico Discovery of Antibodies Targeting Integral Membrane Proteins Combining In Situ Selections of Phage Displayed Synthetic Antibodies and Next-Generation Sequencing

2020-08-04

Abstract excerpt

<title>Abstract</title> <p>Synthetic antibody (Ab) technologies are efficient and cost-effective platforms for the generation of monoclonal proteomic tools against human antigens. Yet, they typically depend on purified proteins, which exclude from interrogation integral membrane proteins that require the lipid bilayers to support their native form or function. Here, we present a novel Ab discovery strategy, terme...

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Literature Corpus work: df311404-a988-55b0-b9e0-8546a5615621
DOI: 10.21203/rs.3.rs-48667/v1

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