Article

EvoBind: peptide binder design with inverse folding and protein structure prediction

2023-01-10

Abstract excerpt

<title>Abstract</title> <p>Protein design requires structural scaffolds generated with human guidance and the performance across known binding domains is not known. Here, we design peptide binders by combining known structural information searched with Foldseek, the protein design method ESM-IF1 and the protein structure prediction method AlphaFold2 (AF) in a joint framework. Foldseek is used to automatically gen...

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Literature Corpus work: 560d7fa4-f8ed-5e79-80f7-308e5411a49c
DOI: 10.21203/rs.3.rs-2385835/v1

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