Article
Data-driven evaluation of suitable immunogens for improved antibody selection
2024-10-11
Abstract excerpt
<h4>ABSTRACT</h4> Antibodies are indispensable in laboratory and clinical applications due to their high specificity and affinity for protein antigens. However, selecting the right protein fragments as immunogens for antibody production remains challenging. Leveraging the Human Protein Atlas, this study systematically evaluates immunogen properties aiming to identify key factors that influence their suitability....
Topics
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- Biosimilars and Bioanalytical Methods
- Glycosylation and Glycoproteins Research
- Monoclonal and Polyclonal Antibodies Research
- Protein purification and stability
- Receptor Mechanisms and Signaling
- RNA and protein synthesis mechanisms
- vaccines and immunoinformatics approaches
- Viral Infectious Diseases and Gene Expression in Insects
Identifiers and source
- Literature Corpus work
- 6e09fb69-38aa-5a3c-95cd-6860ee542010
- DOI
- 10.1101/2024.10.07.617016