Article

Transcriptomic Evidence of MAS1 Receptor Dysregulation and a Failed Compensatory State in Human Vascular Cognitive Impairment

2026-05-17

Abstract excerpt

<h4>Background</h4> Vascular contributions to cognitive impairment and dementia (VCID) are thought to arise from distributed neurovascular unit (NVU) dysfunction rather than focal pathology, yet the transcriptional architecture of human VCID brain tissue and the status of endogenous counter-regulatory signaling within it remain incompletely characterized. Defining whether protective pathways are engaged and why t...

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Literature Corpus work: 640e8a3b-de96-507a-9a8e-133dc195e83f
DOI: 10.64898/2026.05.06.26352482

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