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Accelerated aging-related transcriptome alterations in neurovascular unit cells in the brain of Alzheimer’s disease

18 Aug 2022

Abstract excerpt

Alzheimer's disease (AD) is the most common cause of dementia with no effective therapies. Aging is a dominant risk factor for AD. The neurovascular unit (NVU) plays an important role in maintaining homeostasis of the brain microenvironment. The accelerated aging of NVU cells may directly impair NVU function and contribute to AD pathogenesis. However, the expression patterns of aging-related genes (AGs) in NVU...

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Alzheimer's disease research and treatments
Neuroinflammation and Neurodegeneration Mechanisms
Neurological Disease Mechanisms and Treatments

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36062157
DOI: 10.3389/fnagi.2022.949074

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