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Transcriptomic signatures of individual cell types in cerebral cavernous malformation

9 Jan 2024

Abstract excerpt

Cerebral cavernous malformation (CCM) is a hemorrhagic neurovascular disease with no currently available therapeutics. Prior evidence suggests that different cell types may play a role in CCM pathogenesis. The contribution of each cell type to the dysfunctional cellular crosstalk remains unclear. Herein, RNA-seq was performed on fluorescence-activated cell sorted endothelial cells (ECs), pericytes, and neuroglia...

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Share to Intracerebral and Subarachnoid Hemorrhage Research
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PMID: 38195510
DOI: 10.1186/s12964-023-01301-2

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