Article

Lipid droplet dysmetabolism affects cell homeostasis in an <i>in vitro</i> model of Alzheimer’s disease

2025-06-13

Abstract excerpt

Lipid droplets (LD) are dynamic organelles involved in neutral lipid storage, energy homeostasis, and can prevent lipotoxicity and oxidative distress. LD dysmetabolism has been considered a pathological hallmark in neurodegenerative disorders, including Alzheimer’s disease (AD). In this study, we investigated the alterations in LD metabolism and their impact on mitochondria-associated membranes (MAM) in an in vitr...

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Literature Corpus work: 63fa8e13-a1d6-53bf-a3f5-bf309be26c04
DOI: 10.1101/2025.06.09.658644

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